Clinical Trials

HNCIG Clinical Trials:

Number Study Title Groups Recruitment
HNCIG‑1 Post-operative Adjuvant Treatment for HPV-positive Tumours (PATHOS) NCRI, EORTC Open
HNCIG‑2 EORTC 1420: Study Assessing The “Best of” Radiotherapy vs the “Best of” Surgery in Patients With Oropharyngeal Carcinoma (Best Of) EORTC, SAKK Open
HNCIG‑3 CompARE: Phase III randomised controlled trial Comparing Alternative Regimens for escalating treatment of intermediate and high-risk oropharyngeal cancer NCRI, TMC Open
HNCIG‑4 Determination of Cetuximab Versus Cisplatin Early and Late Toxicity Events in HPV+ OPSCC (De-ESCALaTE) NCRI, Cancer Trials Ireland Open
HNCIG‑5 NRG HN001: Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA NRG Oncology, NCTN, HKNPCSG, Singapore NCC, Fudan University Open
HNCIG‑6 NRG HN002: Reduced-Dose Intensity-Modulated Radiation Therapy With or Without Cisplatin in Treating Patients With Advanced Oropharyngeal Cancer NRG Oncology, NCTN, CCTG Closed to accrual
HNCIG‑7 EORTC-1219-ROG-HNCG: A blind randomized multicenter study of accelerated fractionated chemo-radiotherapy with or without the hypoxic radiosensitizer nimorazole (Nimoral), using a 15 gene signature for hypoxia in the treatment of squamous cell carcinoma of the head and neck EORTC, DAHANCA, TROG Closed to accrual

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